Scientific Software & Data Analysis

Tools that think
in molecules,
atoms and data.

iScience designs and develops analytical software, numerical models and AI-powered tools for chemistry, pharma, life sciences and nuclear.

Process Chemistry Nuclear & Radiation AI & Machine Learning Spectral Analysis DoE & Optimization LIMS
9+
Active tools
4
Core domains
100+
Projects
20+
Years experience
MI
Milano, Italy
20 Years · Project Timeline
2025 108 projects · 4 domains · 9 tools
Sectors Served
100%
all sectors
What we do

Our Services

End-to-end support from algorithm design to production deployment, for research teams and industrial partners.

AI for Data Science

Consultancy for data analysis, numerical modeling and advanced visualization tailored to scientific domains.

Scientific Software

Full life-cycle development of analytical tools, LIMS, and domain-specific desktop and web applications.

Hardware Integration

Embedded systems, parallel computing (GPU/OpenCL) and instrument interfacing for laboratory environments.

Training

Specialized courses in data science, machine learning and scientific computing for research teams.

The i-suite

Technologies

A coherent family of analytical tools sharing the same design language, built for chemists, nuclear scientists and data engineers.

iLAB
Electronic Lab Notebook
ELN · Reagent Mgmt · Analytical

Advanced ELN system flexible enough to fit the workflow of each research partner. Manages reagents, synthesis protocols and analytical data in a unified interface. Incorporates tools for molecular design and computational chemistry integration. iLAB is designed to interoperate natively with the other tools in the i-suite: experimental results can be forwarded directly to iTERA to set up a Design of Experiments campaign, or to iSCALE to initiate a scale-up study. This tight integration turns iLAB into the central hub of a fully connected scientific workflow, from first synthesis to pilot plant.

ELN Multi-technique Mol. Design
iTRACE
Analytical LIMS
NMR · IR · MS · HPLC · GC · UV-Vis

Browser-based laboratory information management system for analytical chemistry. Supports JCAMP-DX, standard chromatography exports and generic tabular formats. Includes peak finder, Gaussian/Lorentzian fitting, and an editable multi-family spectral reference library with server persistence.

JCAMP-DX Peak Fitting Flask Backend Library Editor
iTERA
Chemical DoE Optimizer
Classical DoE · PIML · Bayesian

Design of Experiments tool for process chemistry combining classical methods (Full Factorial, CCD, Box-Behnken, Plackett-Burman) with physics-informed machine learning and Bayesian Optimization. Ranked results view with study management and Flask backend.

Bayesian Opt. PIML Study DB Ranked Results
iSCALE
Process Scale-Up Tool
Lab → Pilot → Plant

Structured scale-up calculator for chemical process engineering. Covers agitation (Reynolds, power number), heat transfer, mass transfer, reaction kinetics, crystallization and more. Each case is computed and logged in a persistent study database for team collaboration.

10 Case Types Engineering Calc. Study Management Flask Backend
iSPEC
Gamma Spectrum Analyzer
CSV · TKA · NPES-v2 · N42

Interactive gamma spectroscopy tool with polynomial energy calibration, peak finder (moving-average baseline), Gaussian/Lorentzian fitting with FWHM and SNR, background subtraction, and isotope matching against public nuclear databases.

Energy Calibration Isotope Matching Peak Fitting Plotly
iRAD
Monte Carlo Radiation Simulation
Gamma · Neutron · Dose · Spectrometry

Full-physics Monte Carlo simulation environment for gamma and neutron transport. Computes dose deposition in detectors and shielding geometries, models detector response functions for gamma spectrometry, and supports nuclide inventory calculations for waste characterization and decommissioning. Seamlessly integrates with iSPEC for end-to-end spectrometric analysis workflows.

Monte Carlo Gamma Physics Neutron Transport Dose Calc. Spectrometry
iNVERA
AI Document Management
Generative AI · Extraction · RAG

Generative AI platform for scientific document management. Automates content extraction, report drafting and summarization. Improves information retrieval by synthesizing insights from unstructured document archives using retrieval-augmented generation.

Generative AI RAG Doc Extraction
iSIM
Agent-Based Modeling
Complex Systems · Simulation

Modeling environment where "objects" populate a scenario and "agents" evolve their position and state over time. Applied to diffusion, percolation, reaction-diffusion and complex system simulation in chemical and nuclear contexts.

Agent-Based Diffusion Monte Carlo
iCHART
Interactive Data Visualization
2D · 3D · nD · ML Trends

Visualization toolkit with dozens of 2D, 3D and n-dimensional chart types. Supports synchronized multi-chart events, interactive infographics and embedded machine learning algorithms for trend analysis and pattern identification.

Multi-chart ML Trends Infographics
Track record

Projects

Selected research and industrial collaborations applying our tools in chemistry, nuclear science and process engineering.

Current

Continuous Flow Optimization — Pharmaceutical Intermediates

Mario Vescovi, Chiara Fontana, Luca Bianchi iTERA · DoE · PIML

Application of iTERA to the optimization of a continuous-flow synthesis of a pharmaceutical intermediate. Classical Box-Behnken design used to screen five process variables (temperature, residence time, flow ratio, catalyst loading, pH), followed by Bayesian Optimization to converge on yield >94% and selectivity >99%. Physics-informed surrogate model validated against kinetic data from in-line analytics.

Current

Radioactive Waste Characterization Campaign — Northern Italy Facility

Mario Vescovi, Elena Marchetti, Roberto Sala iRAD · iSPEC · Dosimetry

Multi-site radiometric characterization of legacy low- and intermediate-level radioactive waste using iRAD for study management and iSPEC for gamma spectral analysis. The campaign defined dose maps and nuclide inventories for 120+ waste packages, supporting decommissioning planning in compliance with IAEA and national regulatory requirements.

Recent

Batch-to-Pilot Scale-Up — Specialty Polymer Synthesis

Mario Vescovi, Andrea Rossi, Giulia Ferretti iSCALE · Heat Transfer · Agitation

Scale-up study from 2 L laboratory reactor to 200 L pilot vessel for a specialty polymer process using iSCALE. Heat transfer and agitation cases identified a critical mixing time discrepancy at scale; the tool guided impeller geometry selection and baffling configuration. Resulting pilot runs achieved product quality equivalent to lab scale with ±3% molecular weight deviation.

Recent

Dose Rate Mapping — Research Reactor Decommissioning

Mario Vescovi, Francesco Neri iRAD · OpenMC · Monte Carlo

Integrated workflow combining iRAD for field measurement management with OpenMC neutron transport calculations to produce dose rate maps in the reactor hall and adjacent rooms during decommissioning operations. iSPEC was used to identify and quantify activation products from structural material samples, feeding nuclide vectors back into the Monte Carlo model for iterative refinement.

Past

Crystallization Process Development — Active Ingredient Scale-Up

Mario Vescovi, Sara Colombo, Matteo De Luca, Valeria Ricci iSCALE · iTERA · Crystallization

Combined iTERA and iSCALE workflow for the development and scale-up of an anti-solvent crystallization process for an active pharmaceutical ingredient. iTERA screened solvent/anti-solvent ratios and cooling profiles via a D-optimal design; iSCALE evaluated mixing and supersaturation profiles at 10 L, 100 L and 1000 L scales, predicting particle size distribution shifts and guiding agitation speed adjustments to maintain crystal habit.

Get in touch

Contacts

Interested in a collaboration or a demo of our tools? Write to us.

Website
Address
Piazza della Repubblica, 1/A
20121 Milano, Italy
P. IVA
06877760964